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Osaka Prefecture will host “Global Startup Crossroads-Osaka,” bringing together international startups, investors, and corporations for four days of intensive business matching September 16-19, 2025. The initiative targets three high-growth sectors: Life Sciences, Carbon Neutral technologies, and Digital innovation (AI/Web3.0).

Key Features:

  • 4 days of concentrated startup networking events
  • 3 strategic sectors with dedicated programming
  • Multiple international conferences including medtech pitch competitions and US-Japan healthcare connections
  • New portal site aggregating all startup events and company profiles in the region

The program coincides with “Global Startup EXPO 2025” at the Expo venue (September 17-18), creating unprecedented access to global startup ecosystem leaders in one location.

This initiative represents the largest coordinated startup networking effort in the Osaka-Kansai region, designed to provide global companies and investors with direct access to Japan’s outstanding startups and the entire regional innovation ecosystem.

Major Events at a Glance

Life Sciences

  • Global Pitch Showdown at Showcase Japan 2025
    September 16, 6:00-10:00 PM | Osaka International Convention Center (Grand Cube Osaka)
    Selected medtech startups from around the world presenting to government agencies, corporations, and investors.
  • U.S.-Japan Healthcare Connection Osaka 2025
    September 19, 9:00 AM-7:00 PM | Nakanoshima Qross
    Healthcare startup networking connecting American and Japanese innovation ecosystems.

Carbon Neutral

  • Osaka Climate Innovation Forum
    September 18, 2:00-6:00 PM | Knowledge Capital Congrès Convention Center
    Climate tech startups with corporations, investors, universities, and international support organizations.

Digital (AI, Web3.0)

  • EDCON2025 & KIDOU Global Conference
    September 18, All Day |Congrès Square Grand Green Osaka
    AI, Web3.0, and digital innovation with international startup and investor participation.

The Osaka-Kansai region has emerged as a critical innovation hub, with particular strengths in life sciences, advanced manufacturing, and digital technologies. This concentrated week of activities provides international startups and local companies access to global innovation and new business opportunities.